Synthesis and biological evaluation of 2,6-di-tert-butylphenol hydrazones as 5-lipoxygenase inhibitors
Authors
Cuadro Palacios, Ana María; Valenciano Martínez, Jesús; Vaquero López, Juan J.; Álvarez-Builla Gómez, Julio; Sunkel Letelier, Carlos; [et al.]Identifiers
Permanent link (URI): http://hdl.handle.net/10017/2701DOI: 10.1016/S0968-0896(97)10018-9
ISSN: 0968-0896
Publisher
Pergamon
Date
1998Bibliographic citation
Bioorganic & Medicinal Chemistry, 1998, v.6, n.2, p.173-180
Keywords
Antigen-induced contraction
Cyclooxygenase inhibitors
Arachidonic-acid
Dual 5-lipoxygenase
Leukotriene-B4
Biosynthesis
Diseases
Trachea
MK-886
Biochemistry & Molecular Biology
Chemistry, Medicinal
Chemistry, Organic
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/S0968-0896(97)10018-9Rights
© Elsevier, 1997
Access rights
info:eu-repo/semantics/openAccess
Abstract
The preparation of hydrazone derivatives of 3,5-di-tert-butyl-4-hydroxybenzaldehyde and the inhibition of 5-lipoxygenase (5-LO) by these compounds is discussed.
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