Function Oriented Molecular Design: Dendrimers as novel antimicrobials
Authors
García Gallego, Sandra; Franci, Gianluigi; Falanga, Annerita; Gómez Ramírez, Rafael; Folliero, Veronica; [et al.]Identifiers
Permanent link (URI): http://hdl.handle.net/10017/35223DOI: 10.3390/molecules22101581
ISSN: 1420-3049
Date
2017-09-11Funders
Junta de Castilla y León
Ministerio de Economía y Competitividad
Bibliographic citation
Molecules, 2017, v. 22, n. 10, p. 1581-
Keywords
dendrimers
structure
preparation
delivery
antimicrobial
antibacterial
antiviral
antiparasitic
Project
info:eu-repo/grantAgreement/MINECO//CTQ-2014-54004-P/ES/DISEÑO DE SISTEMAS DENDRÍTICOS AVANZADOS PARA SU USO EN BIOMEDICINA, OBTENIDOS A TRAVÉS DE PROCESOS DE DENDRONIZACIÓN
info:eu-repo/grantAgreement/Junta de Castilla y León//S2011%2FBMD-2351/ES/Nanosistemas dendríticos como agentes y vectores terapeúticos en distintas aplicaciones biomédicas
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
© MDPI, 2017
Access rights
info:eu-repo/semantics/openAccess
Abstract
In recent years innovative nanostructures are attracting increasing interest and, among them, dendrimers have shown several fields of application. Dendrimers can be designed and modified in plentiful ways giving rise to hundreds of different molecules with specific characteristics and functionalities. Biomedicine is probably the field where these molecules find extraordinary applicability, and this is probably due to their multi-valency and to the fact that several other chemicals can be coupled to them to obtain desired compounds. In this review we will describe the different production strategies and the tools and technologies for the study of their characteristics. Finally, we provide a panoramic overview of their applications to meet biomedical needs, especially their use as novel antimicrobials.
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