Synthesis of degradable cationic carbosilane dendrimers based on Si-O or ester bonds
Authors
Rodríguez Prieto, Tamara; Barrios Gumiel, Andrea; Mata de la Mata, Francisco Javier de la; Sánchez-Nieves Fernández, Javier; Gómez Ramírez, RafaelIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/34059DOI: 10.1016/j.tet.2016.07.084
ISSN: 0040-4020
Publisher
Elsevier
Date
2016-09-29Embargo end date
2018-09-29Funders
Ministerio de Economía y Empresa
Bibliographic citation
Tetrahedron, 2016, v. 72, n. 39, p. 5825-5830
Keywords
Biodegradable dendrimers
Carbosilane dendrimers
Ester bonds
Stability
Project
info:eu-repo/grantAgreement/MINECO//CTQ-2014-54004-P/ES/DISEÑO DE SISTEMAS DENDRÍTICOS AVANZADOS PARA SU USO EN BIOMEDICINA, OBTENIDOS A TRAVÉS DE PROCESOS DE DENDRONIZACIÓN
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/acceptedVersion
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
(c) Elsevier, 2016
Access rights
info:eu-repo/semantics/openAccess
Abstract
Several cationic carbosilane dendrimers have been synthesized containing two different types of degradable
bonds: SieO and ester bonds. The first type of systems was prepared by reacting carbosilane
dendrimers containing peripheral SieCl bonds with first generation dendrons presenting a eOH function
at the focal point and amine peripheral functions. The second type of systems was prepared by esterification
between a dendrimer containing acid groups and an alcoholamine. The stability in water of both
types of cationic systems was evaluated
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