Antibacterial and antifungal properties of dendronized silver and gold nanoparticles with cationic carbosilane dendrons
Autores
Peña González, Cornelia Emeritina; Pedziwiatr-Webicka, Elzbieta; Martín Pérez, Tania; Szewczyk, Eligia Maria; Copa Patiño, José Luis; [et al.]Identificadores
Enlace permanente (URI): http://hdl.handle.net/10017/33959DOI: 10.1016/j.ijpharm.2017.05.067
ISSN: 0378-5173
Editor
Elsevier
Fecha de publicación
2017-08-01Fecha fin de embargo
2018-08-01Filiación
Universidad de Alcalá. Departamento de Biomedicina y Biotecnología; Universidad de Alcalá. Departamento de Química Orgánica y Química InorgánicaPatrocinadores
Ministerio de Economía y Empresa
Cita bibliográfica
International Journal of Pharmaceutics, 2017, v. 528, n. , p. 55-61
Palabras clave
Silver nanoparticles
Gold nanoparticles
Dendrimers and dendrons
Carbosilane
Antibacterial
Antifungal
Proyectos
info:eu-repo/grantAgreement/MINECO//CTQ-2014-54004-P/ES/DISEÑO DE SISTEMAS DENDRÍTICOS AVANZADOS PARA SU USO EN BIOMEDICINA, OBTENIDOS A TRAVÉS DE PROCESOS DE DENDRONIZACIÓN
Tipo de documento
info:eu-repo/semantics/preprint
Versión
info:eu-repo/semantics/submittedVersion
Derechos
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
(c) Elsevier, 2014
Derechos de acceso
info:eu-repo/semantics/openAccess
Resumen
Water soluble silver nanoparticles (AgNPs) capped with cationic carbosilane dendrons have been synthesized by direct reaction in water of dendrons, silver precursor and a reducing agent. These nanoparticles have been characterized by nuclear magnetic resonance (NMR), transmission electron microscopy (TEM), dynamic light scattering (DLS), thermogravimetric analysis (TGA), ultraviolet spectroscopy (UV), elemental analysis, and zeta potential (ZP). The antibacterial and antifungal properties of the cationic dendrons and dendronized AgNPs and AuNPs with these dendrons have been evaluated against Gram-negative and Gram-positive bacterial -including resistant strains- and yeast strains, respectively. The results stand out for the activity of AgNPs covered with first generation dendron compared with this free dendron and corresponding dendronized AuNPs.
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antibacterial_copa_IJP_2017_.pdf | 5.472Mb |
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antibacterial_copa_IJP_2017_.pdf | 5.472Mb |
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