Show simple item record

Selective palladium-catalyzed amination of the heterocyclic core of variolins

dc.contributor.authorBaeza García, Alejandro 
dc.contributor.authorBurgos García, Carolina 
dc.contributor.authorÁlvarez-Builla Gómez, Julio 
dc.contributor.authorVaquero López, Juan J.
dc.date.accessioned2009-04-28T17:24:46Z
dc.date.available2009-04-28T17:24:46Z
dc.date.issued2007
dc.identifier.bibliographicCitationTetrahedron Letters, 2007, v. 48, n. 14, p. 2597-2601en
dc.identifier.issn0040-4039
dc.identifier.urihttp://hdl.handle.net/10017/2652
dc.description.abstractA new and selective palladium-catalyzed amination of the pyrido[3′,3′:4,5]pyrrolo[1,2-c]pyrimidine nucleus, the heterocyclic core of the variolin alkaloids, is described. The method allows the introduction of amino and aryl- and alkylamino substituents on the C9 position in advanced precursors of variolin B and deoxyvariolin.en
dc.description.sponsorshipWe acknowledge financial support from the Spanish Ministerio de Educación y Ciencia (project CTQ2005/011060), Comunidad de Madrid (CAM) and Universidad de Alcalá (UAH) (project CAM/UAH-2005/044) and a grant (A.B.) from the Ministerio de Educación y Ciencia.en
dc.description.sponsorshipComunidad de Madrides_ES
dc.description.sponsorshipMinisterio de Educación y Cienciaes_ES
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherElsevieren
dc.rights(c) Elsevier, 2007en
dc.subjectPyrido[3 ',3 ': 4,5]pyrrolo[1,2-c]pyrimidineen
dc.subjectN-tosylmethyl dichloroformimideen
dc.subjectAminationen
dc.subjectPalladium-catalyzeden
dc.subjectVariolinsen
dc.subjectSponge kirkpatrickia-varialosaen
dc.subjectTosylmethyl isocyanideen
dc.subjectAlkaloidsen
dc.subjectDeoxyvariolin-Ben
dc.subjectAzolopyrimidinesen
dc.subjectMeridianinsen
dc.subjectDerivativesen
dc.subjectChloridesen
dc.subjectOxazolesen
dc.subjectBromidesen
dc.subjectChemistry, Organicen
dc.titleSelective palladium-catalyzed amination of the heterocyclic core of variolinsen
dc.typeinfo:eu-repo/semantics/articleen
dc.subject.ecienciaBioquímicaes_ES
dc.subject.ecienciaBiochemistryen
dc.subject.ecienciaScienceen
dc.subject.ecienciaCienciaes_ES
dc.contributor.affiliationUniversidad de Alcalá. Departamento de Química Orgánica
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.tetlet.2007.02.011
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1016/j.tetlet.2007.02.011
dc.relation.projectIDinfo:eu-repo/grantAgreement/MEC//CTQ2005%2F011060/ES//es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/CAM//CAM%2FUAH-2005%2F044/ES//es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen


Files in this item

Thumbnail
Name:
388.pdf
Size:
150.8Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)