Effects of fasting and refeeding on somatostatin concentration and binding to cytosol from rabbit gastric mucosa
Identificadores
Enlace permanente (URI): http://hdl.handle.net/10017/2363DOI: 10.1136/gut.29.5.642
ISSN: 0017-5749
Editor
Nature Publishing Group
Fecha de publicación
1988Patrocinadores
Instituto de Salud Carlos III
Palabras clave
Somatostatin
Rabbit
Stomach
Mucosa
Proyectos
info:eu-repo/grantAgreement/ISCIII//86%2F911/ES//
Tipo de documento
info:eu-repo/semantics/article
Versión
info:eu-repo/semantics/publishedVersion
Versión del editor
http://dx.doi.org/10.1136/gut.29.5.642Derechos
© BMJ Publishing Group Ltd, 1988
Derechos de acceso
info:eu-repo/semantics/openAccess
Resumen
Somatostatin like immunoreactivity and the density of somatostatin binding sites were measured in stomach (fundus and antrum) from either fed, 12 to 96 hours fasted, or 96 hours fasted plus 48 hours refed rabbits. The somatostatin concentration increased in fundic and antral mucosa after 24 h and reached its highest value after 96 h of fasting. The number of specific somatostatin binding sites with high and low affinity decreased with the duration of fasting. Refeeding of fasted animals resulted in a normalisation to control values of gastric mucosal somatostatin and somatostatin binding.
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Colecciones
- BIOQBM - Artículos [137]