%0 Journal Article 
%A García Ruiz, Carmen
%A Scholtes, Maarten J.
%A Ariese, Freek
%A Gooijer, Cees
%T Enantioselective detection of chiral phosphorescent analytes in cyclodextrin complexes
%D 2005
%@ 0039-9140
%U http://hdl.handle.net/10017/1329
%X Inclusion complexes between camphorquinone (CQ) and cyclodextrins (CDs) in deoxygenated aqueous solutions are shown to exhibit relatively strong room temperature phosphorescence (RTP). Among the various CDs tested, α-CD showed the strongest RTP signals. Interestingly, these signals differed significantly for the two enantiomers of CQ; the phosphorescence lifetime of (+)-CQ was about four times longer than that of (−)-CQ, being 352 ± 16 and 89 ± 6 μs, respectively. This enantiomeric selectivity is attributed to a difference in dissociation rates (competing with the radiative emission process) for the diastereoisomeric inclusion complexes dealt with, which have a 2:1 stoichiometry (α-CD:CQ:α-CD). Time-resolved RTP detection using different delay times enables the determination of the two enantiomers in a mixture without involving a separation technique. The minimum detectable fraction of (+)-CQ in a 2 mM sample was 13%.
%K Camphorquinone
%K Inclusion complex
%K Room temperature phosphorescence
%K Phosphorescence lifetime
%K Ciencia
%K Química analítica e industrial
%K Science
%K Chemistry, analytic and technical
%~ Biblioteca Universidad de Alcala