RT info:eu-repo/semantics/article
T1 In vitro assessment of the bioavailability of bioactive non-extractable polyphenols obtained by pressurized liquid extraction combined with enzymatic-assisted extraction from sweet cherry (Prunus avium L.)  pomace
A1 Domínguez Rodríguez, Gloria
A1 Marina Alegre, María Luisa
A1 Plaza del Moral, Merichel
K1 Pressurized liquid extraction
K1 Enzyme-assisted extraction
K1 Non-extractable polyphenols
K1 Bioavailability
K1 Sweet cherry pomace
K1 Química
K1 Chemistry
AB In vitro digestion and absorption simulation processes of non-extractable polyphenols (NEPs) obtained by pressurized liquid extraction combined with enzymatic-assisted extraction with Promod enzyme (PLE-EAE) from the residue of conventional extraction of sweet cherry pomace were studied. In general, total phenolic and proanthocyanidin contents decreased in each phase of the digestion. However, the antioxidant capacity increased when the digestion process progressed. In addition, the highest total phenolic and proanthocyanidin contents and antioxidant capacity were obtained in the absorbed fraction. NEPs from PLE-EAE extract, digestive fractions, absorbed and unabsorbed fractions were analyzed by ultra-high-performance liquid chromatography coupled to electrospray ionization quadrupole Exactive-Orbitrap mass spectrometry (UHPLC-ESI-Q-Orbitrap-MS). Fifteen NEPs were identified in the intestinal fraction and five in the absorbed fraction after the digestion process. Results obtained in this study define for the first time the bioavailability of antioxidant NEPs obtained from sweet cherry pomace.
SN 0308-8146
YR 2022
FD 2022-08-15
LK http://hdl.handle.net/10017/52250
UL http://hdl.handle.net/10017/52250
LA eng
DS MINDS@UW
RD 24-abr-2024