RT info:eu-repo/semantics/article
T1 Introducing ATR-FTIR Spectroscopy through Analysis of Acetaminophen Drugs: Practical Lessons for Interdisciplinary and Progressive Learning for Undergraduate Students.
A1 Zapata Arráez, Félix
A1 López Fernández, Adrián
A1 Ortega Ojeda, Fernando Ernesto
A1 Quintanilla López, María Gloria
A1 García Ruiz, Carmen
A1 Montalvo García, Gemma
K1 Upper-Division Undergraduate
K1 Undergraduate Research
K1 Analytical Chemistry
K1 Qualitative Analysis
K1 Forensic Chemistry
K1 Hands-On Learning/Manipulatives
K1 Laboratory Equipment/Apparatus
K1 Drugs/Pharmaceuticals
K1 IR Spectroscopy
K1 Chemometrics.
K1 Química
K1 Chemistry
AB Infrared (IR) spectroscopy is a vibrational spectroscopic technique useful in chemical, pharmaceutical, and forensic sciences. It is essential to identify chemicals for reasons spanning from scientific research and academic practices to quality control in companies. However, in some university degrees, graduate students do not get the proficiency to optimize the experimental parameters to obtain the best IR spectra; to correlate the IR spectral bands with the molecular vibrations (chemical elucidation); to have some criteria for any substance identification (especially relevant in quality control to recognize counterfeit); and to apply chemometrics for comparing, visualizing, and classifying the IR spectra. This work presents an experimental laboratory practice for an introductory teaching of the IR instrumental conditions in the identification of substances based on visual spectra comparison and statistical analysis and matching. Then, the selected IR conditions are applied to different commercial drugs, in the solid state or insolution, mostly composed of acetaminophen. Finally, the students apply chemometrics analysis to the IR data. This practice was designed for the training in a chemistry subject for undergraduate students of the chemistry, pharmacy, or forensics degrees, among others related to science, medical, food, or technological sciences.
SN 0021-9584
YR 2021
FD 2021-08-10
LK http://hdl.handle.net/10017/49989
UL http://hdl.handle.net/10017/49989
LA eng
NO Instituto Universitario de Investigación en Ciencias Policiales (IUICP)
DS MINDS@UW
RD 07-jun-2023