RT info:eu-repo/semantics/article
T1 Antibacterial nanocomposites based on thermosetting polymers derived from vegetable oils and metal oxide nanoparticles
A1 Díez Pascual, Ana María
K1 metal oxide nanoparticles
K1 vegetable oils
K1 thermosetting polymers
K1 antibacterial properties
K1 nanocomposites
K1 reactive oxygen species
K1 Chemistry
K1 Química
AB Thermosetting polymers derived from vegetable oils (VOs) exhibit a wide range of outstanding properties that make them suitable for coatings, paints, adhesives, food packaging, and other industrial appliances. In addition, some of them show remarkable antimicrobial activity. Nonetheless, the antibacterial properties of these materials can be significantly improved via incorporation of very small amounts of metal oxide nanoparticles (MO-NPs) such as TiO2, ZnO, CuO, or Fe3O4. The antimicrobial efficiency of these NPs correlates with their structural properties like size, shape, and mainly on their concentration and degree of functionalization. Owing to their nanoscale dimensions, high specific surface area and tailorable surface chemistry, MO-NPs can discriminate bacterial cells from mammalian ones, offering long-term antibacterial action. MO-NPs provoke bacterial toxicity through generation of reactive oxygen species (ROS) that can target physical structures, metabolic paths, as well as DNA synthesis, thereby leading to cell decease. Furthermore, other modes of action-including lipid peroxidation, cell membrane lysis, redox reactions at the NP-cell interface, bacterial phagocytosis, etc.-have been reported. In this work, a brief description of current literature on the antimicrobial effect of VO-based thermosetting polymers incorporating MO-NPs is provided. Specifically, the preparation of the nanocomposites, their morphology, and antibacterial properties are comparatively discussed. A critical analysis of the current state-of-art on these nanomaterials improves our understanding to overcome antibiotic resistance and offers alternatives to struggle bacterial infections in public places.
SN 2073-4360
YR 2019
FD 2019-11-11
LK http://hdl.handle.net/10017/49664
UL http://hdl.handle.net/10017/49664
LA eng
NO Universidad de Alcala
DS MINDS@UW
RD 24-abr-2024