RT info:eu-repo/semantics/article
T1 Nanomaterials in protein sample preparation
A1 Marina Alegre, María Luisa
A1 García López, María Concepción
A1 González García, Estefanía
K1 Protein sample preparation
K1 nanomaterials
K1 extraction
K1 enrichment
K1 purification
K1 digestion
K1 enzyme
K1 Química
K1 Chemistry
AB Protein sample preparation is the most critical step in protein analysis of complex samples and is constituted by tedious, time-consuming, and difficult-to-automate steps that usually involve the use of high volumes of solvents. In recent years, novel extraction or digestion nanomaterials (NMs) have been developed aiming to overcome these drawbacks. In this review, we have grouped the recent works related to the development of new NMs and their applications to the extraction, enrichment/purification, and digestion of proteins. This paper evaluates the role of different kinds of NMs in each step of protein sample preparation focusing on the type of established interaction between the protein and the nanomaterial, their sensitivity and selectivity, their adsorption capacity, and the advantages that they bring in relation to time, efficiency, or reusability.
SN 1542-2119
YR 2020
FD 2020-07-02
LK http://hdl.handle.net/10017/44567
UL http://hdl.handle.net/10017/44567
LA eng
DS MINDS@UW
RD 26-abr-2024