RT info:eu-repo/semantics/article T1 High-performance liquid-chromatographic determination of the pi-values of azol-N-yl substituents A1 Álvarez-Builla Gómez, Julio A1 Crespo, Teresa A1 López, Raquel A1 Elguero, José A1 Toiron, Catherine A1 Yranzo, Gloria I. K1 Hydrophobicity measurements K1 Partition-coefficients K1 Behavior K1 Water K1 Ciencia K1 Química orgánica K1 Science K1 Chemistry, organic AB The π (hydrophobic constant) values for 16 parent azoles (pyrrole, imidazole, pyrazole, four triazoles, two tetrazoles, indole, benzimidazole, 1 H and 2H-indazoles, 1H-and 2H-benzotriazoles, and carbazole) were calculated from the logarithms of the capacity factors (log k′) determined by HPLC. The values thus obtained are discussed according to an additive model in which the number and position of pyridinelike nitrogen atoms and the annelation effect are considered. PB American Pharmacists Association SN 0022-3549 YR 1992 FD 1992 LK http://hdl.handle.net/10017/3920 UL http://hdl.handle.net/10017/3920 LA eng NO J. A. B., T. C., and R.L.acknowledge financial support from the Comisión lnterministerial de Ciencia y Tecnología through project. PB87-0755. DS MINDS@UW RD 29-mar-2024