RT info:eu-repo/semantics/article
T1 Enantioselective detection of chiral phosphorescent analytes in cyclodextrin complexes
A1 García Ruiz, Carmen
A1 Scholtes, Maarten J.
A1 Ariese, Freek
A1 Gooijer, Cees
K1 Camphorquinone
K1 Inclusion complex
K1 Room temperature phosphorescence
K1 Phosphorescence lifetime
K1 Ciencia
K1 Química analítica e industrial
K1 Science
K1 Chemistry, analytic and technical
AB Inclusion complexes between camphorquinone (CQ) and cyclodextrins (CDs) in deoxygenated aqueous solutions are shown to exhibit relatively strong room temperature phosphorescence (RTP). Among the various CDs tested, α-CD showed the strongest RTP signals. Interestingly, these signals differed significantly for the two enantiomers of CQ; the phosphorescence lifetime of (+)-CQ was about four times longer than that of (−)-CQ, being 352 ± 16 and 89 ± 6 μs, respectively. This enantiomeric selectivity is attributed to a difference in dissociation rates (competing with the radiative emission process) for the diastereoisomeric inclusion complexes dealt with, which have a 2:1 stoichiometry (α-CD:CQ:α-CD). Time-resolved RTP detection using different delay times enables the determination of the two enantiomers in a mixture without involving a separation technique. The minimum detectable fraction of (+)-CQ in a 2 mM sample was 13%.
PB Elsevier
SN 0039-9140
YR 2005
FD 2005
LK http://hdl.handle.net/10017/1329
UL http://hdl.handle.net/10017/1329
LA eng
NO C. Garcia-Ruiz gratefully thanks the European Commissionfor a postdoctoral Marie Curie individual fellowship(Contract No. HPMF-CT-2002-01826).
DS MINDS@UW
RD 20-abr-2024