Exploring New Kingdoms: The Role of Extracellular Vesicles in Oxi-Inflamm-Aging Related to Cardiorenal Syndrome
Authors
Alique Aguilar, MatildeIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/51277DOI: 10.3390/antiox11010078
ISSN: 2076-3921
Date
2021-12-29Funders
Instituto de Salud Carlos III
Sociedad Española de Nefrología
Ministerio de Asuntos Económicos y Transformación Digital
Ministerio de Cultura y Deporte
Ministerio de Ciencia e Innovación
Comunidad de Madrid
Bibliographic citation
Mas-Bargues C, Alique M, Barrús-Ortiz MT, Borrás C, Rodrigues-Díez R. Exploring new kingdoms: The role of extracellular vesicles in oxi-inflamm-aging related to cardiorenal syndrome. Antioxidants. 2022;11(1):78.
Keywords
Aging
Oxidative stress
Senescence
Extracellular vesicles
Senolytics
Inflammation
Age-related pathologies
Oxi-inflamm-aging
Project
info:eu-repo/grantAgreement/ISCIII//PI19%2F00240
info:eu-repo/grantAgreement/MINECO//SAF 2015-69295-R
info:eu-repo/grantAgreement/MCD//RAEFEC-URJC 30%2FUPB%2F21
Info:eu-repo/grantAgreement/MCIN/AEI/10.13039%2F501100011033
info:eu-repo/grantAgreement/MINECO//PCIN-2017-117
info:eu-repo/grantAgreement/EC/A Healthy Diet for a Healthy Life /JPI HDHL INTIMIC-085
info:eu-repo/grantAgreement/CAM/AORTASANA-CM/B2017%2FBMD3676
info:eu-repo/grantAgreement/MICINN/PROYECTOS I+D+i/PID2020-113839RB-I00
info:eu-repo/grantAgreement/MICINN/Juan de la Cierva-Incorporación/IJCI-2017-31399
info:eu-repo/grantAgreement/MINECO//SAF-2016-80305-P
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Rights
© 2021 by the authors. Licensee MDPI, Basel, Switzerland
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Access rights
info:eu-repo/semantics/openAccess
Abstract
The incidence of age associated chronic diseases has increased in recent years. Although several diverse causes produce these phenomena, abundant evidence shows that oxidative stress plays a central role. In recent years, numerous studies have focused on elucidating the role of oxidative stress in the development and progression of both aging and chronic diseases, opening the door to the discovery of new underlying mechanisms and signaling pathways. Among them, senolytics and senomorphics, and extracellular vesicles offer new therapeutic strategies to slow the development of aging and its associated chronic diseases by decreasing oxidative stress. In this review, we aim to discuss the role of extracellular vesicles in human cardiorenal syndrome development and their possible role as biomarkers, targets, or vehicles of drugs to treat this syndrome.
Files in this item
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exploring_mas_ANTIOXIDANTS_2021.pdf | 1.371Mb |
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exploring_mas_ANTIOXIDANTS_2021.pdf | 1.371Mb |
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