Recent contributions of Capillary Electrophoresis to neuroscience
Authors
Sánchez López, Elena; Montealegre Dondarza, Cristina; Crego Navazo, Antonio Luis; Marina Alegre, María LuisaIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/48887DOI: 10.1016/j.trac.2014.12.008
ISSN: 0165-9936
Date
2015-04Affiliation
Universidad de Alcalá. Departamento de Química Analítica, Química Física e Ingeniería QuímicaBibliographic citation
TrAC - Trends in Analytical Chemistry, 2015, v. 67, p. 82-99
Keywords
Amino acid
Biogenic amine
Biological sample
Capillary electrophoresis
Chiral capillary electrophoresis
Laser-induced fluorescence
Mice liar electrokinetic chromatography
Neuroactive compound
Neurological disorder
Neuroscience
Project
Universidad de Alcalá (CCG2013 / EXP-065)
info:eu-repo/grantAgreement/MINECO//CTQ2013-48740-P/ES/METODOLOGIAS AVANZADAS PARA ANALISIS QUIRAL MEDIANTE TECNICAS MICROSEPARATIVAS. BUSQUEDA DE BIOMARCADORES EN SISTEMAS ENANTIOSELECTIVOS/
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Rights
Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
© Elsevier
Access rights
info:eu-repo/semantics/openAccess
Abstract
Contributions to neuroscience are necessary to understand the behavior of the brain. Powerful analytical techniques are needed to monitor neuroactive molecules and their concentrations in biological samples (fluids, cells, and brain tissues). Capillary electrophoresis (CE) is well known for its high resolution power, short analysis times, and low consumption of reagents and samples. It presents analytical advantages for the determination of neuroactive molecules not easily determined by other analytical techniques. CE also offers the possibility of controlling more than one neuroactive molecule at a time, making it interesting to detect changes as a result of a stimulus. CE is well established to accomplish enantioseparations, contributing a better understanding of the properties of a neuroactive chiral molecule. This review focuses on the most relevant articles published from January 2008 to July 2014, based on the determination in biological samples of potentially interesting molecules in neuroscience using CE and microchip-CE. (C) 2014 Elsevier B.V. All rights reserved.
Files in this item
Files | Size | Format |
|
---|---|---|---|
Recent_Sanchez_TrAC_2015.pdf | 1.031Mb |
|
Files | Size | Format |
|
---|---|---|---|
Recent_Sanchez_TrAC_2015.pdf | 1.031Mb |
|
Collections
- QUANING - Artículos [367]