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dc.contributor.authorD'Elia, Valentina 
dc.contributor.authorMontalvo García, Gemma 
dc.contributor.authorGarcía Ruiz, Carmen 
dc.date.accessioned2021-04-23T09:15:08Z
dc.date.available2021-04-23T09:15:08Z
dc.date.issued2016-07-01
dc.identifier.bibliographicCitationTalanta, 2016, v. 154, n. 1, p. 367-373en
dc.identifier.issn0039-9140
dc.identifier.urihttp://hdl.handle.net/10017/47448en
dc.description.abstractThe principal objective of this work was to demonstrate the capability of Raman spectroscopy to detectsmall amounts of cocaine in nasal fluid, and to identify the main drug and the most widely used cuttingagents. Initially, standard samples were analysed and sampling conditions were studied by comparingdifferent swabs used for the sample collection. Once the most appropriate swab was selected, whichpermitted a relatively simple detection of the standard cocaine hydrochloride, qualitative analyses of realsamples were carried out. Three street cocaine samples were analysed, and the presence of cuttingsubstances was highlighted by the appearance of different bands not corresponding to the ones of thestandard cocaine. To identify the substances present in each sample, the spectra of the street cocainesamples were collected and compared with a digital library created on purpose with the spectra of themost common cutting agents. In this case, correlation coefficients permitted to recognize the most importantsubstances presumably present in the samples, and gave an estimation of the purity of the cocaine.However, when nasal fluid was present, its strong signal could overlap or interfere with thesmaller signal of the cutting substances, hindering their identification.en
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)en
dc.rights© Elsevier, 2016en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectCocaineen
dc.subjectNasal fluiden
dc.subjectRaman spectroscopyen
dc.subjectCutting agentsen
dc.titleAnalysis of street cocaine samples in nasal fluid by Raman spectroscopyen
dc.typeinfo:eu-repo/semantics/articleen
dc.subject.ecienciaQuímicaes_ES
dc.subject.ecienciaChemistryen
dc.contributor.affiliationUniversidad de Alcalá. Departamento de Química Analítica, Química Física e Ingeniería Químicaes_ES
dc.date.updated2021-04-23T09:08:16Z
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.identifier.doihttp://dx.doi.org/10.1016/j.talanta.2016.03.077en
dc.relation.projectIDCCG2015/EXP-028 (Universidad de Alcalá)es_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.identifier.uxxiAR/0000023180en
dc.identifier.publicationtitleTalantaen
dc.identifier.publicationvolume154
dc.identifier.publicationlastpage373
dc.identifier.publicationissue1
dc.identifier.publicationfirstpage367


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Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
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