Gamma-Carboline Synthesis by Heterocyclization of TosMIC Derivatives

Authors
Gutiérrez Hernández, SaraUniversity of Alcalá Author; Sucunza Sáenz, DavidUniversity of Alcalá Author; Vaquero López, Juan J.
Identifiers
Permanent link (URI): http://hdl.handle.net/10017/43888
DOI: 10.1021/acs.joc.8b00906
ISSN: 0022-3263
Date
2018-06-15
Affiliation
Universidad de Alcalá. Departamento de Química Orgánica y Química Inorgánica
Bibliographic citation
Journal of Organic Chemistry, 2018, v. 83, n. 12, p. 6623-6632
Project
CTQ2014-52488-R y CTQ2017-85263-R (Ministerio de Ciencia), ISCIII RETIC REDINREN RD16/0009/015 FEDER FUNDS (Instituto de Salud Carlos III) y CCGP2017-EXP/003 (Universidad de Alcalá)
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
© American Chemical Society, 2018
Access rights
info:eu-repo/semantics/openAccess
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Abstract
A new method for the synthesis of gamma-carbolines by a heterocyclization that involves alpha-indol-2-ylmethyl TosMIC derivatives and different electrophiles has been developed. This methodology has been successfully applied to the synthesis of several highly substituted gamma-carbolines.
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