dc.contributor.author | Garre Hernández, María Soledad | |
dc.contributor.author | Sucunza Sáenz, David | |
dc.contributor.author | Aguilar, Enrique | |
dc.contributor.author | García García, Patricia | |
dc.contributor.author | Vaquero López, Juan J. | |
dc.date.accessioned | 2020-07-15T10:10:39Z | |
dc.date.available | 2020-07-15T10:10:39Z | |
dc.date.issued | 2019-05-03 | |
dc.identifier.bibliographicCitation | The Journal of Organic Chemistry, 2019, v. 84, n. 9, p. 5712-5725 | en |
dc.identifier.issn | 0022-3263 | |
dc.identifier.uri | http://hdl.handle.net/10017/43792 | en |
dc.description.abstract | Cyclobutane-fused dihydropyrans and methylenetetrahydrofurans are highly interesting cores found in numerous natural products. Both these cores are selectively prepared from a common alkynylcyclobutane precursor bearing an appended hydroxyl group herein. Thus, cyclobutane-fused dihydropyrans can be obtained by a selective 6-endo-dig iodocyclization, whereas gold-catalyzed 5-exo-dig cycloisomerization provides a bicyclic core containing a methylenetetrahydrofuran moiety as major product. Several cyclobutane-fused O-heterocycles with diverse substituents are synthesized following the reported methodology | en |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) | en |
dc.rights | © 2019 American Chemical Society | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en |
dc.subject | Cyclobutane | en |
dc.subject | dihydropyran | en |
dc.subject | methylenetetrahydrofuran | en |
dc.subject | gold | en |
dc.subject | iodine | en |
dc.subject | electrophilic cyclization | en |
dc.title | Regiodivergent Electrophilic Cyclizations of Alkynylcyclobutanes for the Synthesis of Cyclobutane-Fused O-Heterocycles | en |
dc.type | info:eu-repo/semantics/article | en |
dc.subject.eciencia | Química | es_ES |
dc.subject.eciencia | Chemistry | en |
dc.contributor.affiliation | Universidad de Alcalá. Departamento de Química Orgánica y Química Inorgánica | es_ES |
dc.date.updated | 2020-07-15T10:10:11Z | |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.identifier.doi | 10.1021/acs.joc.9b00618 | en |
dc.relation.projectID | CTQ2017-85263-R (Ministerio de Economía y Competitividad, AEI, FEDER); RETIC REDINREN RD16/0009/0015 (Instituto de Salud Carlos III, FEDER); CCG2015/EXP-003 (University of Alcalá) | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MINECO//CTQ2014-58688-R/ES/DESARROLLO DE UNA HERRAMIENTA HIPERESPECTRAL FORENSE PARA UN ANALISIS COMPLETO DE RESIDUOS DE DISPARO EN LA DIANA | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
dc.identifier.uxxi | AR/0000030575 | en |
dc.identifier.publicationtitle | The Journal of Organic Chemistry | en |
dc.identifier.publicationvolume | 84 | |
dc.identifier.publicationlastpage | 5725 | |
dc.identifier.publicationissue | 9 | |
dc.identifier.publicationfirstpage | 5712 | |