A new approach to the synthesis of 2-aminoimidazo[1,2-a]pyridine derivatives through microwave-assisted N-alkylation of 2-halopyridines
Authors
Vega Ramiro, Juan AntonioIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/4206DOI: 10.1016/S0040-4020(99)00012-5
ISSN: 0040-4020
Publisher
Elsevier
Date
1999Funders
CDTI program (Plan concertado 96/0036)
PROFARMA program (Ministerio de Industria y Ministerio de Sanidad)
Bibliographic citation
Tetrahedron, 1999, v.55, n.8, p.2317-2326
Keywords
Focused microwave
Alkylation
2-Halopyridines
Imidazo[1,2-a]pyridines
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/S0040-4020(99)00012-5Rights
© Elsevier, 1999
Access rights
info:eu-repo/semantics/openAccess
Abstract
A microwave (focused waves) assisted N-alkylation of 2-halopyridines provides a convenient entry to 2-amino-imidazo[1,2-a]pyridine derivatives after reaction of the alkylated substrates with cyanamide under basic conditions.
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