dc.contributor.author | Siro Herrero, Jorge G. | |
dc.contributor.author | Ramos González, Andrés | |
dc.contributor.author | Vaquero López, Juan J. | |
dc.contributor.author | Álvarez-Builla Gómez, Julio | |
dc.contributor.author | García Navío, José Luis | |
dc.date.accessioned | 2009-10-02T11:47:03Z | |
dc.date.available | 2009-10-02T11:47:03Z | |
dc.date.issued | 2000 | |
dc.identifier.bibliographicCitation | Tetrahedron, 2000, v.56, n.16, p.2469-2472 | en |
dc.identifier.issn | 0040-4020 | |
dc.identifier.uri | http://hdl.handle.net/10017/4192 | |
dc.description.abstract | By combining two complementary statistical techniques (fractional factorial experimental design and simplex operation) the synthesis of the parent pyrido[1,2-b]-pyridazinium cation has been successfully carried out (the yield was improved from less than 10 to 65%) by basic condensation of 2-methyl-1-aminopyridinium mesitylenesulfonate and [1,4]dioxane-2,3-diol. Using the optimized reaction conditions, other related heterocyclic cations could be prepared, and two interesting examples are now reported. | en |
dc.description.sponsorship | Ministerio de Educación y Ciencia | es_ES |
dc.description.sponsorship | Universidad de Alcalá | es_ES |
dc.format.mimetype | application/pdf | en |
dc.language.iso | eng | en |
dc.publisher | Elsevier | en |
dc.rights | © Elsevier, 2000 | en |
dc.subject | Westphal | en |
dc.subject | Condensations | en |
dc.subject | Polycyclic heterocyclic ions | en_US |
dc.subject | Computer-assisted methods | en |
dc.title | Optimized synthesis of di, tri and tetrafused pyridazinium cations | en |
dc.type | info:eu-repo/semantics/article | en |
dc.subject.eciencia | Ciencia | es_ES |
dc.subject.eciencia | Química orgánica | es_ES |
dc.subject.eciencia | Science | en |
dc.subject.eciencia | Chemistry, organic | en |
dc.contributor.affiliation | Universidad de Alcalá. Departamento de Química Orgánica | |
dc.relation.publisherversion | http://dx.doi.org/10.1016/S0040-4020(00)00079-X | |
dc.type.version | info:eu-repo/semantics/publishedVersion | en |
dc.identifier.doi | 10.1016/S0040-4020(00)00079-X | |
dc.relation.projectID | SAF 98-0093 (Comision Interministerial de Ciencia y Tecnologia-CICYT) | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |