| dc.contributor.author | Álvarez-Builla Gómez, Julio | |
| dc.contributor.author | Crespo, Teresa | |
| dc.contributor.author | López, Raquel | |
| dc.contributor.author | Elguero, José | |
| dc.contributor.author | Toiron, Catherine | |
| dc.contributor.author | Yranzo, Gloria I. | |
| dc.date.accessioned | 2009-09-10T15:46:05Z | |
| dc.date.available | 2009-09-10T15:46:05Z | |
| dc.date.issued | 1992 | |
| dc.identifier.bibliographicCitation | Journal of Pharmaceutical Sciences, 1992 v. 81, n. 6, p. 577-580 | en |
| dc.identifier.issn | 0022-3549 | |
| dc.identifier.uri | http://hdl.handle.net/10017/3920 | |
| dc.description.abstract | The π (hydrophobic constant) values for 16 parent azoles (pyrrole, imidazole, pyrazole, four triazoles, two tetrazoles, indole, benzimidazole, 1 H and 2H-indazoles, 1H-and 2H-benzotriazoles, and carbazole) were calculated from the logarithms of the capacity factors (log k′) determined by HPLC. The values thus obtained are discussed according to an additive model in which the number and position of pyridinelike nitrogen atoms and the annelation effect are considered. | en |
| dc.description.sponsorship | J. A. B., T. C., and R.L.acknowledge financial support from the Comisión lnterministerial de Ciencia y Tecnología through project. PB87-0755. | en |
| dc.format.mimetype | application/pdf | en |
| dc.language.iso | eng | en |
| dc.publisher | American Pharmacists Association | en |
| dc.publisher | Wiley | en |
| dc.rights | (c) American Pharmaceutical Association, 1992 | en |
| dc.subject | Hydrophobicity measurements | en |
| dc.subject | Partition-coefficients | en |
| dc.subject | Behavior | en |
| dc.subject | Water | en |
| dc.title | High-performance liquid-chromatographic determination of the pi-values of azol-N-yl substituents | en |
| dc.type | info:eu-repo/semantics/article | en |
| dc.subject.eciencia | Ciencia | es_ES |
| dc.subject.eciencia | Química orgánica | es_ES |
| dc.subject.eciencia | Science | en |
| dc.subject.eciencia | Chemistry, organic | en |
| dc.contributor.affiliation | Universidad de Alcalá. Departamento de Química Orgánica | |
| dc.relation.publisherversion | http://dx.doi.org/10.1002/jps.2600810623 | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | en |
| dc.identifier.doi | 10.1002/jps.2600810623 | |
| dc.relation.projectID | PB87-0755 (Comisión Interministerial de Ciencia y Tecnología-CICYT) | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
