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Synthesis of L-2-amino-8-oxodecanoic acid: an amino acid component of apicidins

dc.contributor.authorLinares de la Morena, María Lourdes 
dc.contributor.authorAgejas Chicharro, Francisco Javier 
dc.contributor.authorAlajarín Ferrández, Luis Ramón 
dc.contributor.authorVaquero López, Juan J.
dc.contributor.authorÁlvarez-Builla Gómez, Julio 
dc.date.accessioned2009-07-23T12:19:51Z
dc.date.available2009-07-23T12:19:51Z
dc.date.issued2001
dc.identifier.bibliographicCitationSynthesis, 2001, n.12, p.2069-2073en
dc.identifier.issn0039-7881
dc.identifier.urihttp://hdl.handle.net/10017/3680
dc.description.abstractThe synthesis Of L-2-amino-8-oxodecanoic acid (Aoda) is described. This is a rare amino acid component of apicidins, a family of new cyclic tetrapeptides, inhibitors of histone deacetylase. Aoda was synthesised in seven steps from L-glutamic acid along with some derivatives.en
dc.description.sponsorshipUniversidad de Alcaláes_ES
dc.description.sponsorshipFundación General de la Universidad de Alcaláes_ES
dc.description.sponsorshipFEDERes_ES
dc.format.mimetypeapplication/pdfen
dc.language.isoengen
dc.publisherThiemeen
dc.rights© 2001, Georg Thieme Verlagen
dc.subjectAmino aciden
dc.subjectAodaen
dc.subjectApicidinsen
dc.subjectHistone deacetylaseen
dc.subjectInhibitorsen
dc.titleSynthesis of L-2-amino-8-oxodecanoic acid: an amino acid component of apicidinsen
dc.typeinfo:eu-repo/semantics/articleen
dc.subject.ecienciaCienciaes_ES
dc.subject.ecienciaQuímica orgánicaes_ES
dc.subject.ecienciaScienceen
dc.subject.ecienciaChemistry, organicen
dc.contributor.affiliationUniversidad de Alcalá. Departamento de Química Orgánica
dc.relation.publisherversionhttp://dx.doi.org/10.1055/s-2006-942395
dc.type.versioninfo:eu-repo/semantics/publishedVersionen
dc.identifier.doi10.1055/s-2006-942395
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen


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