Synthesis and reactivity of N-alkyl-2-oxoalkanesulfonamides
Authors
Vega Ramiro, Juan Antonio; Alajarín Ferrández, Luis Ramón; Vaquero López, Juan J.; Álvarez-Builla Gómez, JulioIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/3508DOI: 10.1016/S0040-4020(98)00093-3
ISSN: 0040-4020
Publisher
Pergamon
Date
1998Bibliographic citation
Tetrahedron, 1998, v.54, n.14, p.3589-3606
Keywords
Suifonamide group
Stereoselectivity
Radioselectivity
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/S0040-4020(98)00093-3Rights
© Elsevier, 1998
Access rights
info:eu-repo/semantics/openAccess
Abstract
A series of N-alkyl-2-oxoalkanesulfonamides have been synthesized by reacting silyl enol ethers with N-alkyl-sulfamoyl chlorides. Their reactivity towards electrophiles was investigated in order to explore the regio-and stereoselectivity of the process. 2-Oxoalkanesulfonamides were used to prepare 5-(methylsulfamoyl)-1,4-dihydropyridines derivatives.
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