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Antibacterial and antifungal properties of dendronized silver and gold nanoparticles with cationic carbosilane dendrons

dc.contributor.authorPeña González, Cornelia Emeritina 
dc.contributor.authorPedziwiatr-Webicka, Elzbieta
dc.contributor.authorMartín Pérez, Tania 
dc.contributor.authorSzewczyk, Eligia Maria
dc.contributor.authorCopa Patiño, José Luis 
dc.contributor.authorSoliveri de Carranza, Juan 
dc.contributor.authorPérez Serrano, Jorge 
dc.contributor.authorGómez Ramírez, Rafael 
dc.contributor.authorBryszewska, Maria
dc.contributor.authorSánchez-Nieves Fernández, Javier 
dc.contributor.authorMata de la Mata, Francisco Javier de la 
dc.date.accessioned2018-07-24T12:55:35Z
dc.date.issued2017-08-01
dc.identifier.bibliographicCitationInternational Journal of Pharmaceutics, 2017, v. 528, n. , p. 55-61en
dc.identifier.issn0378-5173
dc.identifier.urihttp://hdl.handle.net/10017/33959
dc.description.abstractWater soluble silver nanoparticles (AgNPs) capped with cationic carbosilane dendrons have been synthesized by direct reaction in water of dendrons, silver precursor and a reducing agent. These nanoparticles have been characterized by nuclear magnetic resonance (NMR), transmission electron microscopy (TEM), dynamic light scattering (DLS), thermogravimetric analysis (TGA), ultraviolet spectroscopy (UV), elemental analysis, and zeta potential (ZP). The antibacterial and antifungal properties of the cationic dendrons and dendronized AgNPs and AuNPs with these dendrons have been evaluated against Gram-negative and Gram-positive bacterial -including resistant strains- and yeast strains, respectively. The results stand out for the activity of AgNPs covered with first generation dendron compared with this free dendron and corresponding dendronized AuNPs.en
dc.description.sponsorshipMinisterio de Economía y Empresaes_ES
dc.format.mimetypeapplication/pdfen
dc.language.isoeng
dc.publisherElsevieren
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.rights(c) Elsevier, 2014
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectSilver nanoparticlesen
dc.subjectGold nanoparticlesen
dc.subjectDendrimers and dendronsen
dc.subjectCarbosilaneen
dc.subjectAntibacterialen
dc.subjectAntifungalen
dc.titleAntibacterial and antifungal properties of dendronized silver and gold nanoparticles with cationic carbosilane dendronsen
dc.typeinfo:eu-repo/semantics/preprinten
dc.subject.ecienciaQuímicaes_ES
dc.subject.ecienciaChemistryen
dc.contributor.affiliationUniversidad de Alcalá. Departamento de Biomedicina y Biotecnologíaes_ES
dc.contributor.affiliationUniversidad de Alcalá. Departamento de Química Orgánica y Química Inorgánicaes_ES
dc.date.updated2018-07-23T09:56:34Z
dc.type.versioninfo:eu-repo/semantics/submittedVersionen
dc.identifier.doi10.1016/j.ijpharm.2017.05.067
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//CTQ-2014-54004-P/ES/DISEÑO DE SISTEMAS DENDRÍTICOS AVANZADOS PARA SU USO EN BIOMEDICINA, OBTENIDOS A TRAVÉS DE PROCESOS DE DENDRONIZACIÓNes_ES
dc.date.embargoEndDate2018-08-01
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen
dc.identifier.uxxiAR/0000026436
dc.identifier.publicationtitleInternational Journal of Pharmaceuticsen
dc.identifier.publicationvolume528
dc.identifier.publicationlastpage61
dc.identifier.publicationfirstpage55


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