Synthesis and cytotoxic activity of pyridazino[1 ',6 ': 1,2] pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents
Authors
Fontana, Alberto; Benito Molinero, Enrique JavierIdentifiers
Permanent link (URI): http://hdl.handle.net/10017/2799DOI: 10.1016/S0960-894X(02)00472-9
ISSN: 0960-894X
Publisher
Pergamon
Date
2002Bibliographic citation
Bioorganic & Medicinal Chemistry Letters, 2002, v.12, n.18, p.2611-2614
Keywords
Fused benzimidazolium salts
DNA intercalating agents
System
Chemistry, Medicinal
Chemistry, Organic
Project
SAF98–0093 (Comisión Interministerial de Ciencia y Tecnologı́a-CICYT)
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/S0960-894X(02)00472-9Rights
© Elsevier, 2002
Access rights
info:eu-repo/semantics/openAccess
Abstract
Several new pyridazino[1′,6′:1,2]pyrido[3,4-b]indol-5-inium derivatives were synthesised from β-carboline derivatives and their cytotoxic activity and effect on the cell cycle were evaluated against L1210 cancer cells.
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