Synthesis and cytotoxic activity of pyridazino[1 ',6 ': 1,2] pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents

Authors
Fontana, Alberto; Benito Molinero, Enrique JavierUniversity of Alcalá Author; Martín Gutierrez, Justina; Sánchez, Nuria; Alajarín Ferrández, Luis RamónUniversity of Alcalá Author; [et al.]
Identifiers
Permanent link (URI): http://hdl.handle.net/10017/2799
DOI: 10.1016/S0960-894X(02)00472-9
ISSN: 0960-894X
Publisher
Pergamon
Date
2002
Affiliation
Universidad de Alcalá. Departamento de Química Orgánica
Bibliographic citation
Bioorganic & Medicinal Chemistry Letters, 2002, v.12, n.18, p.2611-2614
Keywords
Fused benzimidazolium salts
DNA intercalating agents
System
Chemistry, Medicinal
Chemistry, Organic
Project
SAF98–0093 (Comisión Interministerial de Ciencia y Tecnologı́a-CICYT)
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/S0960-894X(02)00472-9
Rights
© Elsevier, 2002
Access rights
info:eu-repo/semantics/openAccess
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Abstract
Several new pyridazino[1′,6′:1,2]pyrido[3,4-b]indol-5-inium derivatives were synthesised from β-carboline derivatives and their cytotoxic activity and effect on the cell cycle were evaluated against L1210 cancer cells.
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