Palladium-catalysed amination of 2-acyl-1-alkyl-5-bromopyrroles

Authors
Castellote Álvaro, María IsabelUniversity of Alcalá Author; Vaquero López, Juan J.; Álvarez-Builla Gómez, JulioUniversity of Alcalá Author
Identifiers
Permanent link (URI): http://hdl.handle.net/10017/2680
DOI: 10.1016/j.tetlet.2003.11.029
ISSN: 0040-4039
Publisher
Elsevier
Date
2004
Affiliation
Universidad de Alcalá. Departamento de Química Orgánica
Funders
Financial support from the Comisión Interministerial de Ciencia y Tecnologı́a (CICYT, project BQU2001-1508) is gratefully acknowledged.
Bibliographic citation
Tetrahedron Letters, 2004, v. 45, n. 4, p. 769-772
Keywords
Palladium
Catalysed
Amination
Functionalised
2-Halopyrroles
Pyrrolodiazines
Derivatives
Chemistry
Chemistry, Organic
Project
BQU2001-1508 (Comisión Interministerial de Ciencia y Tecnología-CICYT)
Document type
info:eu-repo/semantics/article
Version
info:eu-repo/semantics/publishedVersion
Publisher's version
http://dx.doi.org/10.1016/j.tetlet.2003.11.029
Rights
(c) Elsevier, 2003
Access rights
info:eu-repo/semantics/openAccess
Share
 
Abstract
The first intermolecular C–N bond-forming reactions between substituted 2-bromopyrroles and primary and cyclic secondary amines were performed using Pd2(dba)3 as catalyst with BINAP as the ligand. The aminations proceeded in the presence of NaOtBu at 80–100 °C in 31–93% yields.
Files in this item
Collections