| dc.contributor.author | Baeza García, Alejandro | |
| dc.contributor.author | Burgos García, Carolina | |
| dc.contributor.author | Álvarez-Builla Gómez, Julio | |
| dc.contributor.author | Vaquero López, Juan J. | |
| dc.date.accessioned | 2009-04-28T17:24:46Z | |
| dc.date.available | 2009-04-28T17:24:46Z | |
| dc.date.issued | 2007 | |
| dc.identifier.bibliographicCitation | Tetrahedron Letters, 2007, v. 48, n. 14, p. 2597-2601 | en |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | http://hdl.handle.net/10017/2652 | |
| dc.description.abstract | A new and selective palladium-catalyzed amination of the pyrido[3′,3′:4,5]pyrrolo[1,2-c]pyrimidine nucleus, the heterocyclic core of the variolin alkaloids, is described. The method allows the introduction of amino and aryl- and alkylamino substituents on the C9 position in advanced precursors of variolin B and deoxyvariolin. | en |
| dc.description.sponsorship | We acknowledge financial support from the Spanish Ministerio de Educación y Ciencia (project CTQ2005/011060), Comunidad de Madrid (CAM) and Universidad de Alcalá (UAH) (project CAM/UAH-2005/044) and a grant (A.B.) from the Ministerio de Educación y Ciencia. | en |
| dc.format.mimetype | application/pdf | en |
| dc.language.iso | eng | en |
| dc.publisher | Elsevier | en |
| dc.rights | (c) Elsevier, 2007 | en |
| dc.subject | Pyrido[3 ',3 ': 4,5]pyrrolo[1,2-c]pyrimidine | en |
| dc.subject | N-tosylmethyl dichloroformimide | en |
| dc.subject | Amination | en |
| dc.subject | Palladium-catalyzed | en |
| dc.subject | Variolins | en |
| dc.subject | Sponge kirkpatrickia-varialosa | en |
| dc.subject | Tosylmethyl isocyanide | en |
| dc.subject | Alkaloids | en |
| dc.subject | Deoxyvariolin-B | en |
| dc.subject | Azolopyrimidines | en |
| dc.subject | Meridianins | en |
| dc.subject | Derivatives | en |
| dc.subject | Chlorides | en |
| dc.subject | Oxazoles | en |
| dc.subject | Bromides | en |
| dc.subject | Chemistry, Organic | en |
| dc.title | Selective palladium-catalyzed amination of the heterocyclic core of variolins | en |
| dc.type | info:eu-repo/semantics/article | en |
| dc.subject.eciencia | Bioquímica | es_ES |
| dc.subject.eciencia | Biochemistry | en |
| dc.subject.eciencia | Science | en |
| dc.subject.eciencia | Ciencia | es_ES |
| dc.contributor.affiliation | Universidad de Alcalá. Departamento de Química Orgánica | |
| dc.relation.publisherversion | http://dx.doi.org/10.1016/j.tetlet.2007.02.011 | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | en |
| dc.identifier.doi | 10.1016/j.tetlet.2007.02.011 | |
| dc.relation.projectID | CTQ2005/011060 (Ministerio de Educación y Ciencia) | |
| dc.relation.projectID | CAM/UAH-2005/044 (Comunidad de Madrid) | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | en |
