%0 Journal Article 
%A Altarejos Salido, Julia
%A Sucunza Sáenz, David
%A Vaquero López, Juan J.
%A Carreras Pérez Aradros, Javier
%T Enantioselective Copper-Catalyzed Synthesis of Trifluoromethyl-Cyclopropylboronates
%D 2021
%@ 1523-7060
%U http://hdl.handle.net/10017/49328
%X A copper-catalyzed enantioselective cyclopropanation involving trifluorodiazoethane in the presence of alkenyl boronates has been developed. This transformation enables the preparation of 2-substituted-3-(trifluoromethyl)cyclopropylboronates with high levels of stereocontrol. The products are valuable synthetic intermediates by transformation of the boronate group. This methodology can be applied to the synthesis of novel trifluoromethylated analogues of trans-2-arylcyclopropylamines, which are prevalent motifs in biologically active compounds.
%K (Trifluoromethyl)cyclopropylboronates
%K Enantioselective cyclopropanation
%K Trifluorodiazoethane
%K Alkenyl boronates
%K Copper catalysis
%K Trifluoromethylcyclopropanes
%K Química
%K Chemistry
%~ Biblioteca Universidad de Alcala