%0 Journal Article 
%A Soto Mayer, Laura
%T Phytochemical Analysis of the methanolic extract of tigernut, tuber of Cyperus esculentus, by ultra-high performance liquid chromatography coupled with electrospray ionization-quadrupole-time of flight-mass spectrometry (UHPLC/ESI-Q-TOF-MS)

%D 2019
%U http://hdl.handle.net/10017/46230
%X In the present work a Spanish local variety of Cyperus esculentus (chufa Appellation of origin
Spanish province of Valencia) was studied. The main phenolic compound profile of chufas was
obtained using ultra high performance liquid chromatography coupled to a quadrupole-timeof-flight mass spectrometry (UHPLC/ESI-Q-TOF-MS). The assayed chromatographic method
enables a rapid and extraordinary efficient separation, allowing easy identification of the
three main phenolic compound groups present in the methanolic extracts: phenylethanoids,
phenylpropanoids and flavonoids. We also investigated, for the characterization of some
other compounds, the possibility of using of in-source fragmentation (ISF) with electrospray
ionization (ESI) followed by product ion scan in the QTOF mass spectrometer system. This
approach is based on the elucidation of the various fragmentation pathways by further
dissociation of each fragment ion in the ion spectrum. This can be achieved predominately,
by combining fragmentor voltage induced dissociation (in-source fragmentation IS-CID) with
subsequent collision-induced dissociation (CID). 37 compounds (3 amino acids and
derivatives, 6 phenolic acids and derivatives, 16 flavonoids, and 8 fatty acids) were
either unambiguously indentified or tentatively characterized. One, N-malonyl-Ltryptophan, identified for the first time in tigernut.
%K Farmacia
%K Pharmacy
%~ Biblioteca Universidad de Alcala