%0 Journal Article 
%A Garre Hernández, María Soledad
%A Sucunza Sáenz, David
%A Aguilar, Enrique
%A García García, Patricia
%A Vaquero López, Juan J.
%T Regiodivergent Electrophilic Cyclizations of Alkynylcyclobutanes for the Synthesis of Cyclobutane-Fused O-Heterocycles
%D 2019
%@ 0022-3263
%U http://hdl.handle.net/10017/43792
%X Cyclobutane-fused dihydropyrans and methylenetetrahydrofurans are highly interesting cores found in numerous natural products. Both these cores are selectively prepared from a common alkynylcyclobutane precursor bearing an appended hydroxyl group herein. Thus, cyclobutane-fused dihydropyrans can be obtained by a selective 6-endo-dig iodocyclization, whereas gold-catalyzed 5-exo-dig cycloisomerization provides a bicyclic core containing a methylenetetrahydrofuran moiety as major product. Several cyclobutane-fused O-heterocycles with diverse substituents are synthesized following the reported methodology
%K Cyclobutane
%K dihydropyran
%K methylenetetrahydrofuran
%K gold
%K iodine
%K electrophilic cyclization
%K Química
%K Chemistry
%~ Biblioteca Universidad de Alcala